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Mesopotamian Journal of Artificial Intelligence in Healthcare

Abstract

Electronic health records (EHRs) are not designed for continuous physiological streams, dynamic patient-state representations, and verifiable cross-provider exchange. This study presents an integrated healthcare architecture combining Internet of Medical Things (IoMT) telemetry, patient-specific Digital Twins, GRU-based risk analytics, blockchain-anchored provenance, and HL7 FHIR R4 interoperability. Its central contribution is the Synchronized State Update with Risk-Aware Blockchain Anchoring (SSU-RABA) algorithm, which couples Digital Twin synchronization with predicted clinical risk to prioritize asynchronous provenance anchoring without blocking the real-time update path. In controlled experiments with 18,000 synthetic IoMT packets, the Digital Twin achieved a mean update latency of 178 ms and synchronization accuracy above 97%, while blockchain verification overhead remained below 50 ms and all tested FHIR resources passed validation. External five-fold subject-independent validation on the BIDMC PPG and Respiration Dataset (53 patients; 24,273 windows) yielded a GRU AUC-ROC of 96.6% and recall of 87.1%; XGBoost achieved an AUC-ROC of 97.6% with higher precision but lower recall. These results show that the proposed architecture can combine low-latency state synchronization, predictive analytics, tamper-evident provenance, and standards-based interoperability under the evaluated conditions. Clinical deployment and prospective validation remain future work.

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